AIDSmeds founder Peter Staley interviewed Dr. Donald Kotler, chief of gastroenterology at St. Luke's-Roosevelt Hospital in New York, and a longtime researcher of wasting, lipodystrophy, and metabolic problems in people with HIV. Kotler discusses TH-9507, an experimental drug for reducing fat around the gut; Fosamax helping with bone loss in HIVers; high-fat diets in people with HIV; and whether lipid-lowering drugs work well for HIVers.