A Smart + Strong Site
Subscribe to:
E-newsletters
POZ magazine
JOIN AIDSMEDS YouTube

Back to home » Treatment News » Top Stories

Most Popular Stories
An Almost Normal Life Expectancy for People With HIV?
Undetectable Viral Load Essentially Eliminates Transmission Risk in Straight Couples
A 15-Year Jump in Life Expectancy for People With HIV
Misleading News Reports Suggest HIV Cure Is Near
New HIV Drug Class Shows Promise
Gene Therapy Shows Promise in Controlling HIV
Potential Microbicide Tricks HIV Into Sudden Death
What's That Mean?
(just double-click it!)

If you don't understand one of the words in this article, just double-click it. A window will open with a definition from mondofacto's On-line Medical Dictionary. If the double-click feature doesn't work in your browser, you can enter the word below:

Most Popular Lessons
Aging & HIV
The HIV Life Cycle
Shingles
Herpes Simplex Virus
Syphilis & Neurosyphilis
Treatments for Opportunistic Infections (OIs)
What is AIDS & HIV?
More News

Have medical or treatment news about HIV? Send press releases, news tips and other announcements to news@aidsmeds.com.

Click here for more news


emailprint

November 28, 2012

High-Dose Vitamins Don’t Fight HIV and Can Raise Liver Levels

A large study has found that high doses of multivitamin supplements fail to combat HIV and may raise liver levels in those also taking antiretrovirals (ARVs), aidsmap reports.  Researchers from the Harvard School of Public Health published the results of their randomized, double-blind, controlled trial in The Journal of the American Medical Association.

The Harvard team recruited 3,418 HIV-positive people in seven clinics in Dar es Salaam, Tanzania, who were beginning ARV treatment between November 2006 and November 2008. Participants took daily oral supplements of either the recommended daily allowance of vitamin B complex, vitamin C and vitamin E, or between two and 21 times the dose of B vitamins, twice the dose of vitamin C and six times that of vitamin E.   

The study was halted early, in March 2009, because patients taking the high vitamin doses experienced elevated alanine transaminase (ALT) levels—which is an indication of liver damage. At that time, 3,418 people were still enrolled in the study for a median 15 months. High-dose vitamins had no effect on CD4 count, viral load, body mass index, mortality, or the risk of the blood disorders anemia and neutropenia.  However, 38 percent of participants in the high-dose arm experienced ALT levels that were elevated five times or greater than the upper limits of normal. Only 2 percent of those in the standard-dose arm experienced such elevations. 
The researchers noted that previous studies have shown that high doses of vitamins are safe for HIV-positive people, but because of “potential negative interactions among nutrients and antiretrovirals” the study authors advised those on ARVs to only take the standard dose of multivitamins.

To read the aidsmap report, click here.

To read the study abstract, click here.

Search: HIV, vitamins, high-dose, Harvard School of Public Health, antiretrovirals, Journal of the American Medical Association, Dar es Salaam, Tanzania, vitamin B complex, vitamin E, vitamin C, alanine transaminase, ALT, CD4 count, anemia, neutropenia, body mass index, viral load.


Scroll down to comment on this story.



Name:

(will display; 2-50 characters)

Email:

(will NOT display)

City:

(will display; optional)

Comment (500 characters left):

(Note: The AIDSmeds team reviews all comments before they are posted. Please do not include ":" "@" "<" ">" in your comment. The opinions expressed by people providing comments are theirs alone. They do not necessarily reflect the opinions of Smart + Strong, which is not responsible for the accuracy of any of the information supplied by people providing comments.)

Comments require captcha.
Please enter this number for verification:

| Posting Rules



Show comments (0 total)


[Go to top]

Quick Links
AIDSmeds en Español
About HIV and AIDS
Lab Tests
Clinical Trials
HIV Meds
Starting Treatment
Switching Treatment
Drug Resistance
Side Effects
Disclosure
Lipodystrophy
Hepatitis & HIV
Women & Children
Fact Sheets
Treatment News
Community Forums
Blogs
Conference Coverage
Health Services Directory
POZ Magazine


    dlw8585
    Fort Lauderdale
    Florida


    romanticseattle
    Tacoma
    Washington


    usuallyhappy
    Palm Springs
    California


    jap022964
    el dorado
    Arkansas
Click here to join POZ Personals!
Conference Coverage

21st Conference on Retroviruses and Opportunistic Infections
(CROI 2014)
Boston, MA
March 3 - 7, 2014


7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention
(IAS 2013)
Kuala Lumpur, Malaysia
June 30 - July 3, 2013


20th Conference on Retroviruses and Opportunistic Infections
(CROI 2013)
Atlanta, GA
March 3 - 7, 2013


more conference coverage

[ about AIDSmeds | AIDSmeds advisory board | our staff | advertising policy | advertise/contact us]
© 2014 Smart + Strong. All Rights Reserved. Terms of use and Your privacy.
Smart + Strong® is a registered trademark of CDM Publishing, LLC.