Among people living with HIV and AIDS, the prevalence of fatigue is quite high. In two studies, 54 and 67 percent of people reported fatigue as a symptom at some point during their course of disease. People with HIV are more likely to suffer from fatigue that interferes with their daily activities than people not infected with the virus. One team of researchers found that when compared with persons not infected with HIV, those with HIV were more likely to be unemployed, to feel fatigued for more hours of the day, to sleep and nap more, and to have a lower level of morning alertness.
Even among people living with HIV, the prevalence of fatigue differs: those with more advanced disease (lower CD4 cell count and/or history of opportunistic infections) are more likely to experience fatigue.
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