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Lesson Changes to Your Face (Facial Lipoatrophy)
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Where are fillers injected?

Skin is not just a simple flat sheet, but is composed of several layers: the epidermis, the dermis, and the hypodermis. The epidermis is the outer layer of skin. The dermis contains fibroblasts (cells that produce fibrous connective tissues including collagen), hair follicles, sebaceous (oil) glands, apocrine (scent) glands, blood vessels, and nerves. The hypodermis, or subcutaneous layer, contains the fat cells that help to give the skin shape and thickness, along with larger blood vessels. The loss of fat in the hypodermis is what causes lipoatrophy.

Facial fillers involve either the dermis or the hypodermis. Most facial fillers involve injections into the dermis, to thicken the skin. Some facial fillers involve injections into the hypodermis to fill the space once held by fat. Because these layers are only millimeters thick, expertise is required to ensure that the injections are performed safety and that the product is injected or inserted into the correct layer of skin.


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Last Revised: April 20, 2006

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