A Smart + Strong Site
Subscribe to:
Newsletters
POZ magazine
JOIN AIDSMEDS YouTube

Back to home » Treatment News » Top Stories

Most Popular Stories
Undetectable Viral Load Essentially Eliminates Transmission Risk in Straight Couples
FDA Approves New Single-Tablet HIV Regimen, Triumeq
Life Expectancy for Young People With HIV Is Nearly Normal
A 15-Year Jump in Life Expectancy for People With HIV
Scientists Devise Method of Snipping HIV From Immune Cells
Monkey HIV Vaccine Success Opens Door for Human Trials
HIV Combo Pill Less Toxic Thanks to New Form of Tenofovir
What's That Mean?
(just double-click it!)

If you don't understand one of the words in this article, just double-click it. A window will open with a definition from mondofacto's On-line Medical Dictionary. If the double-click feature doesn't work in your browser, you can enter the word below:

Most Popular Lessons
Aging & HIV
The HIV Life Cycle
Shingles
Herpes Simplex Virus
Syphilis & Neurosyphilis
Treatments for Opportunistic Infections (OIs)
What is AIDS & HIV?
More News

Have medical or treatment news about HIV? Send press releases, news tips and other announcements to news@aidsmeds.com.

Click here for more news


emailprint

March 14, 2013

Factors Associated With Poor Physical Function in Middle Aged Positive People

Impaired physical function in middle aged people living with HIV are associated with low levels of muscle mass, bone mineral density and insulin levels—the same factors typically linked to frailty in elderly people in the general population. Publishing their findings in the online edition of the Journal of Acquired Immune Deficiency Syndromes, researchers examined 30 “low-functioning” people with HIV and a control group of 48 high-functioning HIV-positive individuals matched for age, gender and length of time since diagnosis with the virus. The aim was to study the connection between body composition and functional impairment, about which there is little knowledge.

The cohort had a mean age of 53 years old and a mean CD4 level of 600; in addition, 96 percent of the participants had an undetectable viral load. All were taking antiretrovirals (ARVs). There was no major difference between the low- and high-functioning groups in their CD4 levels, the duration of their infection or the type of ARVs they took.

Lower T-scores at the hip increased the odds of low functioning by a factor of 3.8, and low T-scores in the lumbar spine did so by a factor of 2.3. Lower bone mineral density in the hip increased the odds of low functioning by a factor of 2.4, and such measurements in the lumbar spine did so by a factor of 2.1. Lower insulin-like growth hormone (IGF-1) increased the odds of low functioning five-fold, and IGF-1 binding protein 3 increased the odds 3.3-fold. Neither fat mass nor vitamin D levels increased the likelihood of low functional status. Those in the study with low physical function were 2.5 times more likely to have low levels of lean muscle mass than those in the high functioning group.

To read the aidsmap story, click here.

To read the study abstract, click here.

Search: poor physical function, muscle mass, bone mineral density, insulin, ournal of Acquired Immune Deficiency Syndromes, T-score, lumbar spine, hip, vitamin D.


Scroll down to comment on this story.



Name:

(will display; 2-50 characters)

Email:

(will NOT display)

City:

(will display; optional)

Comment (500 characters left):

(Note: The AIDSmeds team reviews all comments before they are posted. Please do not include ":" "@" "<" ">" in your comment. The opinions expressed by people providing comments are theirs alone. They do not necessarily reflect the opinions of Smart + Strong, which is not responsible for the accuracy of any of the information supplied by people providing comments.)

Comments require captcha.
Please enter this number for verification:

| Posting Rules



Show comments (0 total)


[Go to top]

Quick Links
About HIV and AIDS
The Cure
Lab Tests
Clinical Trials
HIV Meds
Starting Treatment
Switching Treatment
Drug Resistance
Side Effects
Disclosure
Lipodystrophy
Hepatitis & HIV
Women & Children
Fact Sheets
Treatment News
Community Forums
Blogs
Conference Coverage
Health Services Directory
POZ Magazine


    dversescott
    Baltimore
    Maryland


    juliar33
    brooklyn
    New York


    Deelight4u
    BROOKLYN
    New York


    Fergie911
    Chicago
    Illinois
Click here to join POZ Personals!
Conference Coverage

XX International AIDS Conference
(AIDS 2014)
Melbourne, Australia
July 20 - 25, 2014


21st Conference on Retroviruses and Opportunistic Infections
(CROI 2014)
Boston, MA
March 3 - 7, 2014


7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention
(IAS 2013)
Kuala Lumpur, Malaysia
June 30 - July 3, 2013


more conference coverage

[ about AIDSmeds | AIDSmeds advisory board | our staff | advertising policy | advertise/contact us]
© 2014 Smart + Strong. All Rights Reserved. Terms of use and Your privacy.
Smart + Strong® is a registered trademark of CDM Publishing, LLC.