A Smart + Strong Site
Subscribe to:
POZ magazine

Back to home » Treatment News » Top Stories

Most Popular Stories
An Almost Normal Life Expectancy for People With HIV?
Undetectable Viral Load Essentially Eliminates Transmission Risk in Straight Couples
A 15-Year Jump in Life Expectancy for People With HIV
Misleading News Reports Suggest HIV Cure Is Near
New HIV Drug Class Shows Promise
Gene Therapy Shows Promise in Controlling HIV
Potential Microbicide Tricks HIV Into Sudden Death
What's That Mean?
(just double-click it!)

If you don't understand one of the words in this article, just double-click it. A window will open with a definition from mondofacto's On-line Medical Dictionary. If the double-click feature doesn't work in your browser, you can enter the word below:

Most Popular Lessons
Aging & HIV
The HIV Life Cycle
Herpes Simplex Virus
Syphilis & Neurosyphilis
Treatments for Opportunistic Infections (OIs)
What is AIDS & HIV?
More News

Have medical or treatment news about HIV? Send press releases, news tips and other announcements to news@aidsmeds.com.

Click here for more news


July 13, 2009

Hep C Doubles Risk for AIDS Illnesses

People coinfected with both HIV and hepatitis C virus (HCV) have double the risk of developing an AIDS defining illness (ADI) as people infected with only HIV, according to a study published online July 10 in Clinical Infectious Diseases.

Numerous studies have demonstrated that HIV greatly accelerates HCV disease progression. It is a lot less clear, however, what impact HCV has on HIV disease progression. Studies have been mixed. Few studies have looked at the potential for an increased risk of developing an ADI in coinfected people.

To determine the risk of ADIs in coinfected individuals, Antonella d’Arminio, MD, at the University of Milan, and her colleagues examined the medical records of 5,397 HIV-positive patients in the ICONA Foundation Study Cohort. Most of the patients enrolled in the cohort in 1998, but some were enrolled as recently as 2008. Of those patients, 2,421 were also infected with HCV, and 2,976 were not. The average CD4 count was 418 in the coinfected group and 458 in the group without HCV infection. Roughly one third were women.

There were 496 ADIs in the two groups. The rate of developing an ADI was two-fold higher in the coinfected group, after adjusting for other risk factors. The rate of ADIs was three times as high for developing fungal infections, wasting, dementia and bacterial infections such as tuberculosis and Mycobacterium avium complex (MAC). People taking antiretroviral (ARV) therapy were less likely to develop an ADI than people not taking ARV therapy. People with more severely damaged livers (cirrhosis) were also more likely to have an ADI.

The authors conclude that coinfected people should be more carefully monitored for AIDS defining illnesses.

Search: Hepatitis C, AIDS, fungal infections, Tuberculosis, Mycobacterium avium complex, MAC

Scroll down to comment on this story.


(will display; 2-50 characters)


(will NOT display)


(will display; optional)

Comment (500 characters left):

(Note: The AIDSmeds team reviews all comments before they are posted. Please do not include ":" "@" "<" ">" in your comment. The opinions expressed by people providing comments are theirs alone. They do not necessarily reflect the opinions of Smart + Strong, which is not responsible for the accuracy of any of the information supplied by people providing comments.)

Comments require captcha.
Please enter this number for verification:

| Posting Rules

Show comments (0 total)

[Go to top]

Quick Links
AIDSmeds en Español
About HIV and AIDS
Lab Tests
Clinical Trials
HIV Meds
Starting Treatment
Switching Treatment
Drug Resistance
Side Effects
Hepatitis & HIV
Women & Children
Fact Sheets
Treatment News
Community Forums
Conference Coverage
Health Services Directory
POZ Magazine

    Fort Lauderdale


    New York

Click here to join POZ Personals!
Conference Coverage

21st Conference on Retroviruses and Opportunistic Infections
(CROI 2014)
Boston, MA
March 3 - 7, 2014

7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention
(IAS 2013)
Kuala Lumpur, Malaysia
June 30 - July 3, 2013

20th Conference on Retroviruses and Opportunistic Infections
(CROI 2013)
Atlanta, GA
March 3 - 7, 2013

more conference coverage

[ about AIDSmeds | AIDSmeds advisory board | our staff | advertising policy | advertise/contact us]
© 2014 Smart + Strong. All Rights Reserved. Terms of use and Your privacy.
Smart + Strong® is a registered trademark of CDM Publishing, LLC.